Finally tired of his nearly-century-long struggle against the Tennyson family, Vilgax, whose body is on its last legs as his prosthetics and various other enhancements are damaged beyond repair, decides to shed his mortal form once and for all, and in his ultimate plan, unleashes himself as a plague across Earth, where he ultimately reigns triumphant against Earth's current defender, Julius Tennyson. With the Bio-Core in his possession, he swiftly works to rewrite reality as he sees fit, causing multiple universes to collide.